Tacrolimus induces glomerular injury via endothelial dysfunction caused by reactive oxygen species and inflammatory change.

Kengo Kidokoro,Minoru Satoh,Hajime Nagasu,Takeo Sakuta,Atsunori Kuwabara,Daisuke Yorimitsu,Yuko Nishi,Naruya Tomita,Tamaki Sasaki,Naoki Kashihara

Tacrolimus induces glomerular injury via endothelial dysfunction caused by reactive oxygen species and inflammatory change.

2012

Kengo Kidokoro
Minoru Satoh
Hajime Nagasu
Takeo Sakuta
Atsunori Kuwabara
Daisuke Yorimitsu
Yuko Nishi
Naruya Tomita
Tamaki Sasaki
Naoki Kashihara

Background/Aims: The immunosuppressive drug tacrolimus (FK506) is used clinically to reduce the rejection rate in patients with kidney transplantation; however, t

Keywords:

Kidney transplantation
Endocrinology
NAD(P)H oxidase
Oxidative stress
Pharmacology
Internal medicine
Nephrotoxicity
Endothelial dysfunction
Tacrolimus
Immunosuppressive drug
Medicine
Reactive oxygen species
Telmisartan
Oxidase test
NAD+ kinase

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