Cell Resistant Peptidomimetic Poly (2-ethyl-2-oxazoline) Coatings Developed by Low Pressure Inductively Excited Pulsed Plasma Polymerization for Biomedical Purpose
2015
In the present work, for the first time, nano-thick peptidomimetic coatings were developed
using a LP inductively excited pulsed plasma polymerization of 2-ethyl-2-oxazoline (ppEtOz) to
control the cell-surface interactions for biological applications. The different ppEtOz coated
surfaces were investigated by FTIR-ATR, XPS, Ellipsometric, and WCA analysis. Using Gaussian
deconvolution method for IR spectra, we compared the modifications obtained in the chemical
compositions for ppEtOz coated samples obtained under different plasma parameters. It was
found that the amide I/amide II ratios decreased
as the effective plasma power increased, which in
turn decreased the surface hydrophilicity for
ppEtOz coatings. Cell repellent properties of the
ppEtOz coatings deposited at Peff¼1W and 2.5W
were achieved.
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