Prolonged QRS and QTc interval and mortality

To the editor: Breidthardt et al 1 found that patients with acute decompensated heart failure (HF) presenting to their emergency department with prolonged QRS interval (⩾120 ms) showed higher long-term mortality. This is a pathophysiologically plausible finding: after initially representing a marker of diseased myocardium, prolonged QRS may itself subsequently contribute to disease progression.2 Nevertheless, we cannot totally agree with the clinical implication the authors make …