Method for preparing particles or amorphous nanometric scale using solid fat as a solvent

A method for preparing nanoscale particles or amorphous, comprising the steps of: (1) preparing a mixture comprising one or more active ingredients and solid fat as a solvent and (2) pressurizing the mixture comprising one or more active ingredients and fat solid at critical or lower pressure by adding the gas of a supercritical mixture fluid, and then removing the solid fat from the mixture by releasing the solid fat together with the gas of the supercritical fluid, wherein the temperature within the reactor in step ( 2) it is below the melting point of the solid fat contained in the solution prepared in step (1) mixture, and wherein the solid fat is a fat or fat blend that maintain the solid phase at the temperature of 30 ° C or less and having 40 ~ 150 ° C melting point.