A 35-year effective treatment of catecholaminergic polymorphic ventricular tachycardia with propafenone
2019
Key Teaching Points
• Despite proven catecholaminergic polymorphic ventricular tachycardia (CPVT) with pathogen RyR2 mutation and recurrent syncope, patients could have a favorable long-term outcome over 35 years under treatment.
• Propafenone could be effective for treatment of patients with CPVT.
• The beneficial effect of the monotherapy with propafenone in our patient may result from the combined antiarrhythmic effect of this drug with Na+ channel blockade and beta blocker capabilities.
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