Early effect of surgery for ischemic mitral insufficiency: a report of 46 cases

Objective　To investigate early effect of coronary artery bypass grafting (CABG) combined with mitral valve replacement or repair for ischemic mitral regurgitation (insufficiency). Methods　The clinical data of 46 patients with ischemic mitral regurgitation hospitalized in Cardiovascular Department of General Hospital of PLA from December 2006 to November 2011 were retrospectively analyzed. Among the 46 patients, there were 34 males and 12 females, aged 66.8±76.4 years, and 16 of them received CABG combined with mitral valve replacement, and 30 received CABG combined with mitral valve repair. The left ventricular diameter (LVD) and left ventricular ejection fraction (LVEF) of each patient were determined before and after operation. Results　One patient receiving CABG combined with mitral valve replacement died of early postoperative heart failure, and the remaining 45 patients were cured. Seven days after operation, the echocardiography showed a significant reduction of LVD (from 51.8±10.4 mm to 46.8±8.1mm, P<0.05), but no significant difference in LVEF before and after operation (53.43%±11.6% and 54.3%±10.1%, respectively) was found. Conclusion　The early outcome of CABG combining mitral valve surgery for ischemic mitral regurgitation is satisfactory, but further follow-up is still needed for evaluating the long-term results.