Delayed gastric emptying following distal pancreatectomy: incidence and predisposing factors.

Abstract Background Delayed gastric emptying (DGE) following elective distal pancreatectomy (DP) is poorly known. This study aimed to report incidence of DGE following DP, to identify its predisposing factors, and to assess its impact on hospital stay. Methods Patients who had elective DP without additional organ or vascular resection (2012-2017) in two academic hospitals were included. Factors predisposing to DGE, defined according to the International Study Group of Pancreatic Surgery, were identified by multivariate analysis. A systematic review was performed to evaluate DGE incidence following elective DP. Results 311 elective DPs were performed. Three perioperative mortalities (1.0%) were unrelated to DGE. DGE occurred in 31 (10.0%) patients (grade A=21, grade B=7, grade C=3) with a median hospital stay of 16 (13–22) days versus 10 (7–14) without DGE (p 75 years (OR=4.32 [1.53–12.19]; p=0.006), open approach (OR=2.97 [1.1–8]; p=0.031) and POPF grade B-C (OR=2.54 [1.05–6.1]; p = 0.038). The systematic review identified 7 series including 876 patients with an overall 8.1% DGE incidence. Conclusions DGE complicates around 10% of elective DP. Laparoscopic approach and prevention of POPF should be encouraged to reduce DGE incidence.