Complete Genome Sequence of the Treponema pallidum subsp. pallidum Sea81-4 Strain

ABSTRACT Using the rabbit model of syphilis, the Sea81-4 strain of Treponema pallidum subsp. pallidum has been found to be more likely than other strains to invade the central nervous system (CNS). To identify possible explanations for this important phenotype at the genomic level, we sequenced the Sea81-4 strain genome.