Studies on the Effects of Pulsed Magnetic Field on wound healing in Wistar Rats

The wound healing properties of Pulsating Magnetic Field (PMF) therapy are evaluated in this study. In Pulsed Magnetic Field electrical energy is used to produce a series of magnetic pulses of low frequency and intensity through injured tissues whereby each magnetic pulse induces a tiny electrical signal that stimulates cellular repair. The normal healing process manifest in four stages 1. Debridement 2. Contraction 3. Epithelialisation 4. Remodelling. This study characterises the biomechanical changes that occur when standard cutaneous wounds are exposed to radiofrequency pulsed magnetic fields with specific dosage parameters in an attempt to determine whether the functional strength could be accelerated in wound healing. By exposing the wound to PMF of very low frequency and intensity it was found that the healing process could be accelerated. At our centre a four coil assembly has been fabricated and connected to a function generator which supplied a pulsating electric current or sine wave mode to the coil to treat small animals. Two groups of Wistar rats namely Group I and Group II containing eight animals in each group for whom a circular wound was created to the dorsal area of 1 cm diameter. Group I animals serve as control leaving to natural healing and Group II as experimental animals which is subjected to Pulsed Magnetic Field therapy daily for 30 minutes for the period of 30 days. Daily measurement of the wound area was noted in each animal in both groups on a butter paper and the rate of healing calculated and represented graphically. It was seen that the experimental group which received PMF showed a statistically significant difference in rate of healing process than the control group which received no PMF.