Synthesis, Spectral Correlations and Antimicrobial Activities of some 2-Hydroxyphenyl-Styrylketone

Some 2’-hydroxyphenylchalcones have been synthesized under microwave irradiation by ClaisenSchmidt condensation between substituted 2-hydroxyacetophenone and substituted benzaldehydes using catalytic amount of SiO 2-H3PO 4. These chalcones were established by their physical constants and spectroscopic data published earlier. The UV, IR, 1 H NMR and 13 C NMR spectral data of these chalcone have correlated with Hammett substituent constants, F and R parameters. All the compounds have been subjected to screened for antimicrobial activity.