Yeast strain converting quinuclidone into R-3-quinuclidinol and conversion method thereof

The invention relates to a yeast strain for producing R-3-quinuclidinol by using quinuclidone and a production method thereof. The related yeast strain is rhodotorula rubra Rhodotorula rubra X15 which is preserved in China General Microbial Culture Preservation Management Center at present, and the preserving number of the yeast strain is CGMCC No: 3664. The production method adopts the following steps of: 1, activating and culturing seeds; 2, performing starter propagation; and 3, taking fermented culture solution, performing centrifugal collection and washing bacteria, adding a substrate of quinuclidone hydrochloride, adding glucose, reacting for 72 to 84 hours on a table, evaporating the solution to dryness, dissolving and stirring by using dichloromethane, filtering undissolved substances, performing distillation on the solvent under reduced pressure, and obtaining a white solid of R-3-quinuclidinol. Due to the adoption of the method, the high-yield and high-purity R-3-quinuclidinol can be obtained; and the production method has the advantages of no environmental disruption and low energy consumption.