GW26-e3875 Diabetes Blunt the Compensatory Enhancement of SUMOylation Intensity of Sarcoplasmic Reticulum Calcium-transporting ATPase After Myocardial Infarction

Diabetes is an independent risk factor of heart failure and mortality after myocardial infarction(MI). The activity and expression of Sarcoplasmic Reticulum Calcium-transporting ATPase (SERCA2a) decrease in diabetes, leading to diastolic and systolic dysfunction of myocardium. It was recently