Comparison of Topical 0.03% Tacrolimus in Almond and Linseed Oil to Treat Experimentally Induced Keratoconjunctivitis Sicca in Rabbits

Keratoconjunctivitis sicca (KCS), or dry eye syndrome, is a common inflammatory disease of the ocular surface in animals and humans that is characterized by quantitative and/or qualitative tear change. The quantitative alterations are due to an aqueous component deficiency, and the qualitative alterations are due to a lipid or mucin layer deficiency that results in the instability of the pre-corneal tear film.