Preoperative Chemoradiotherapy with Capecitabine and Oxaliplatin in Locally Advanced Rectal Cancer. A Phase I–II Multicenter Study of the Dutch Colorectal Cancer Group

Geke A.P. Hospers,Cornelis J.A. Punt,Margot E. Tesselaar,Annemieke Cats,Klaas Havenga,Jan-Willem Leer,Corrie A.M. Marijnen,Edwin P.M. Jansen,Han van Krieken,Theo Wiggers,Cornelis J. H. van de Velde,Nanno Mulder

Preoperative Chemoradiotherapy with Capecitabine and Oxaliplatin in Locally Advanced Rectal Cancer. A Phase I–II Multicenter Study of the Dutch Colorectal Cancer Group

2007

Geke A.P. Hospers
Cornelis J.A. Punt
Margot E. Tesselaar
Annemieke Cats
Klaas Havenga
Jan-Willem Leer
Corrie A.M. Marijnen
Edwin P.M. Jansen
Han van Krieken
Theo Wiggers
Cornelis J. H. van de Velde
Nanno Mulder

Background We studied the maximum tolerated dose (MTD) and efficacy of oxaliplatin added to capecitabine and radiotherapy (Capox-RT) as neoadjuvant therapy for rectal cancer.

Keywords:

Fluorouracil
Capecitabine
Total mesorectal excision
Chemoradiotherapy
Colorectal cancer
General surgery
Neoadjuvant therapy
Radiation therapy
Oxaliplatin
Medicine
Oncology
Internal medicine
Rectum

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