Prognostic value of modified lung ultrasound aeration loss score in shock patient in intensive care unit

Objective To investigate the prognostic value of modified lung ultrasound aeration loss score(mLUS) in shock patients in intensive care unit(ICU). Methods This was a prospective study.Shock patients who were admitted to ICU from April 2016 to August 2016 were eligible; 90 consecutive shock patients were enrolled.Chest ultrasound examination were done within the first 6 hours after included. The mLUS and other ultrasound variables were recorded as well as the clinical data and the outcome. Data has been analyzed, and a bivariate logistic regression model was established to identify the correlation between mLUS on admission and the ICU mortality. Results The mean APACHE Ⅱ score, lactate, mLUS were significantly increased in non-survivors while the PaO2/FiO2 was decreased in these patients(P=0.048, 0.000, 0.048, 0.000, 0.004). The univariate analysis revealed that the above variables were significantly related to ICU mortality.The multivariate analysis demonstrated that mLUS are the independent risk factors of ICU mortality as well as the lactate(P=0.045, 0.006; AUC=0.733, 0.793, respectively). Conclusion Modified lung ultrasound aeration loss score can predict the outcome of shock patients in ICU. Key words: Shock; Ultrasoundgraphy; Prognosis; Lung aeration loss score