회색 조랑말에서 발생한 악성 흑색종 증례

A 16 year-old female grey pony was presented to Animal and Plant Quarantine agency for diagnosis in Feb 2, 2015. At necropsy, multiple pigmented masses, likely melanomas, were detected peri-anally and under the tail. Further metastatic spread to the spleen, liver, lung and lymph nodes was also identi-fied. Histopathologically, anaplastic and pleomorphic melanocytes were observed in the mass. By im-munohistochemistry, PNL2, S100 and PGP 9.5 protein were detected, but Melan A was not expressed in the neoplastic melanocytes. Based on the pathological and immunohistochemical examination, we di-agnosed this case as malignant melanoma in a grey pony. To the authors` knowledge, this is the first report of equine malignant melanoma in republic of Korea.