Аллергический ринит и феномен энтопии

This article provides a review of the phenomenon of entopy or local atopy from the viewpoint of allergic phenotypes and endotypes. A clinical form of the entopy endotype is local allergic rhinitis, which is still a fertile area for research. The exact mechanisms in the breakdown of allergen tolerance in entopy remain unclear. The  review focuses on the pathogenesis, diagnostic algorithm, and the choice of treatment strategies in local allergic rhinitis.