Prevalence, diagnosis and treatment status of pediatric drug-resistant tuberculosis

Tuberculosis is a chronic infectious disease caused by Mycobacterium tuberculosis, which threats the health of children worldwide.Accompany with the increase of drug-resistance tuberculosis, great challenging has arose in the prevention and treatment of tuberculosis.Nowadays, the diagnosis and treatment of drug-resistance tuberculosis is still difficult in pediatric patients.Based on molecular diagnosis, fast detect as well as reliable treatment of drug-resistance tuberculosis become available.Currently, the principle of drug-resistant tuberculosis treatment in children is essentially similar to adults.In this review, the mechanism, diagnosis and treatment of pediatric drug resistance tuberculosis were discussed. Key words: Child; Drug-resistance tuberculosis; Prevalence; Mechanisms of drug-resistance; Diagnosis; Treatment