P-5m-Fc fusion protein and expression gene thereof, and preparation method and applications of P-5m-Fc fusion protein

The invention relates to a P-5m-Fc fusion protein and an expression gene thereof, and a preparation method and applications of the P-5m-Fc fusion protein, and belongs to the technical field of medicine and biology. The P-5m-Fc fusion protein is formed by linking a functional unit and the Fc portion of human immunoglobulin IgG1, wherein the functional unit is formed by linking an amino acid sequence represented by SEQ ID NO.1 and a connexon, the connexon is a polypeptide formed by six sequentially-linked glycines, the P-5m-Fc fusion protein has at least one functional unit, and when the P-5m-Fc fusion protein has a plurality of the functional units, the plurality of the functional units are sequentially linked, and then are linked to the Fc portion of immunoglobulin. According t the present invention, with the P-5m-Fc fusion protein, P-5m and the Fc portion of the human IgG1 are subjected to fusion expression to prepare the peptide, such that the efficacy of the P-5m octapeptide can be increased, the half-life of the drug can be significantly prolonged, the good patent medicine property is obtained, and the experiment results prove that the significant anti-tumor-metastasis function is provided.