Influence of Threonine Metabolism on S-Adenosylmethionine and Histone Methylation

mice (figs.S10A,S11,andS12).Moreover,JNK deficiencyreduced chemokine expression by macrophagesin vitro under a variety of stimulation conditions(figs. S10B and S13 to S15). Because tissuechemokine expression is mediated by both pa-renchymalcellsand macrophages, it is likely thatthe reduced chemokine expression detected inHFD-fed F