Detection and Analysis of T Lymphocyte Subsets and B Lymphocytes in Patients with Acute Leukemia

题目: 急性白血病患者T、B淋巴细胞的检测与分析. 目的: 探讨不同类型的急性白血病患者外周血T淋巴细胞亚群、B淋巴细胞和NK细胞等在疾病的不同时期的变化及其临床意义。. 方法: 采用流式细胞术检测95例初诊白血病患者[急性淋巴细胞白血病（ALL）43例，急性髓系白血病（AML）52例]诱导治疗前后及50例正常对照者外周血T淋巴细胞亚群、B淋巴细胞、NK细胞及Treg细胞百分比。. CONCLUSION: Changes of T lymphocyte subsets, B lymphocytes and NK cells in the patients with newly diagnosed acute leukemia are significant, thus the detection of T lymphocyte cell subsets, B lymphocytes and NK cells can provide some evidences. for evaluation of the disease severity, curative efficiency and prognosis of patients with acute leukemia. 结论: 初诊白血病各组T淋巴细胞亚群、B淋巴细胞和NK细胞的变化明显，完全缓解组的上述指标基本恢复正常，说明T淋巴细胞亚群、B淋巴细胞、NK细胞水平检测在评价急性白血病严重程度、疗效及判断患者预后有一定的临床价值。.