Ligand-controlled Interaction of HBO1 with the N-terminal Transactivating Domain of Progesterone Receptor Induces SRC-1-dependent Co-activation of Transcription

Ligand-controlled Interaction of HBO1 with the N-terminal Transactivating Domain of Progesterone Receptor Induces SRC-1-dependent Co-activation of Transcription Maria Georgiakaki, Nathalie Chabbert-Buffet, Boris Dasen, Geri Meduri, Sandra Wenk, Leila Rajhi, Larbi Amazit, Anne Chauchereau, Curt.W. Burger, Leen J. Blok, Edwin Milgrom, Marc Lombes, Anne Guiochon-Mantel and Hugues Loosfelt From INSERM, U693 , Recepteurs Steroidiens, Physiopathologie Endocrinienne et Metabolique, Faculte de Medecine Paris-Sud, 63 rue Gabriel Peri, 94276 Le Kremlin-Bicetre Cedex, France. Address for A.G-M, B.D., G.M., H.L., L.R, M.G., M.L., S.W.: INSERM, U693 , Faculte de Medecine Paris-Sud, 63 rue Gabriel Peri, 94276 Le Kremlin-Bicetre, France ; for A.C. : CNRS, UPR9079, Institut Andre Lwoff, 7 rue Guy Moquet 94800 Villejuif, France; for E.M. : Biochimie Hormonale, Hopital de Bicetre, 78 avenue du General Leclerc, 94275 Le Kremlin-Bicetre, France ; for L.A. : Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030 ; for N.C-B Unite de Medecine Vasculaire, Hopital Tenon APHP, 4 rue de la Chine, 75020 Paris, France; for L.J.B., C.W.B. : Department of Reproduction & Development and Obstetrics & Gynaecology, Erasmus University Medical Center, PO Box 1738, 3000 DR Rotterdam, The Netherlands. . CORRESPONDING AUTHOR : Hugues Loosfelt, INSERM, U693, Faculte de Medecine Paris-Sud, 63 rue Gabriel Peri, 94276 Le Kremlin-Bicetre Cedex, France. Tel. 33-(0)1 49 59 67 02; Fax 33-(0)1 49 59 67 32; Email hugues.loosfelt@kb.u-psud.fr