Varicella vaccination for HIV-infected children

Human immunodeficiency virus (HIV)-infected children are more likely to develop severe varicella and to die when infected than otherwise healthy children.1 2 In the absence of universal immunisation varicella remains prevalent.3 Secondary prophylaxis in exposed high-risk patients is expensive, invasive, carries the risk of side-effects and may not be implemented reliably. Primary prophylaxis with live-attenuated varicella vaccine has been shown to be safe and immunogenic and effective against both primary varicella and zoster recurrences in HIV-infected children …