Numb inhibits cell proliferation, invasion, and epithelial–mesenchymal transition through PAK1/β-catenin signaling pathway in ovarian cancer

Jiabin Liang,Bingbing Han,Yunhe Zhang,Qingfen Yue

Numb inhibits cell proliferation, invasion, and epithelial–mesenchymal transition through PAK1/β-catenin signaling pathway in ovarian cancer

2019

Jiabin Liang
Bingbing Han
Yunhe Zhang
Qingfen Yue

Objective The present study aimed to investigate the expression of Numb in ovarian cancer tissues and to assess the effect of Numb on cell proliferation, invasion, and EMT in ovarian cancer.

Keywords:

Ovarian cancer
PAK1
Cancer research
Pathology
NUMB
Catenin
Epithelial–mesenchymal transition
Cell growth
Signal transduction
Medicine
Downregulation and upregulation
Gene silencing

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