C-106T Polymorphism in Promoter of Aldose Reductase Gene Is a Risk Factor for Diabetic Nephropathy in Type 2 Diabetes Patients with Poor Glycaemic Control

Gosek K,Moczulski D,Ewa Zukowska-Szczechowska,Grzeszczak W

C-106T Polymorphism in Promoter of Aldose Reductase Gene Is a Risk Factor for Diabetic Nephropathy in Type 2 Diabetes Patients with Poor Glycaemic Control

2005

Gosek K
Moczulski D
Ewa Zukowska-Szczechowska
Grzeszczak W

Background: Excessive flux through the polyol pathway has long been thought to be involved in the pathogenesis of diabetic microvascular complications. Aldose reductase (AR) is the

Keywords:

Internal medicine
Endocrinology
Aldose reductase
Diabetic nephropathy
Risk factor
Pathogenesis
Polyol pathway
Type 2 diabetes
Polymorphism (computer science)
Biology
Diabetes mellitus

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