Properties and Positional Specificity of Lipases in the Human Aorta

The presence of lipase in the human aortic wall was demonstrated by Adams et al. (Adams et al., 1969). A detailed study on the properties of the enzyme was reported by Hayase and Miller (Hayase et al., 1970). However, they used the whole aortic tissue for preparing the enzyme sources. In this paper studies on the properties of lipases in the human aortic intima and media and on the role of these enzymes in the development of atherosclerosis are presented.