Hadamard Transform Time-of-Flight Spectroscopy

Abstract : This report describes the implementation of a new form of time-of-flight mass spectrometry based upon beam modulation and imaging detection which can be applied to studies of continuous ion beams requiring fast data acquisition rates over a large mass-to-charge ratio range. In addition, the use of the imaging detector in this method allows collection of mass-to-charge resolved movies of an ion beam. The capabilities of this method are demonstrated in studies of ion fragmentation reactions, biochemical kinetics, and the fundamental limitations of desorption electrospray ionization.