The effectiveness of nutritional risk assessment and interventions in patients with oral cancer
2019
Objective
To evaluate the effect of nutritional risk screening and interventions on postoperative nutritional status in patients with oral cancer.
Methods
A total of 83 oral cancer patients with mild or moderate nutritional risk rated by patient-generated subjective global assessment(PG-SGA) from January 2015 to June 2017 were randomized into an experimental group(43 cases) and a control group (40 cases). The patients in the experimental group received 2-week nutritional intervention before the operation,while the patients in the control group received routine preoperative treatment and diet guidance. The biochemical measurements of postoperative nutritional indicators, peripheral blood immunoglobulin indicators, postoperative complications and hospital stays were compared between the two groups.
Results
The levels of prealbumin, retinol-binding protein, total lymphocyte count and transferrin were (218.5±34.6) mg/L, (23.5±4.3) μg/L, (1.82±0.45)×109/L, (2.07±0.63) μg/L on the day of admission in the experimental group, and at 1 day before the operation were (237.3±36.5) mg/L, (27.7±4.8) μg/L, (2.02±0.39)×109/L, (2.43±0.54) μg/L, there was no significant difference(P<0.05). IgM, IgG, IgA at 1 day before the operation were significantly higher than those on the day of admission in the experimental group(P<0.05), and the levels of prealbumin, retinol-binding protein, total lymphocyte count,transferrin, IgM, IgG, IgA and body mass index at 8 days after the operation in the experimental group were significantly higher than those in the control group(t=1.574-3.418, P<0.05). The total rate of postoperative complications was 11.6% (5/43) in the experimental group, 30.0% (12/40) in the control group, and there was significant difference between the two groups (χ2=6.840, P<0.01). The incidence of infection-associated complications such as pneumonia and incision infection was 7.0% (3/43) in the experimental group, 20.0%(8/40) in the control group, and there was significant difference between the two groups (χ2= 5.096, P<0.05).
Conclusions
Preoperative nutritional support can effectively improve the perioperative nutritional status,decrease postoperative complications and operative risk in esophageal cancer patients with mild or moderate nutritional risk.
Key words:
Mouth neoplasms; Preoperative care; Nutritional support
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