Destiffening effect of valsartan and atenolol: influence of heart rate and blood pressure.

Objective:We investigated data in 373 patients from the EXPLOR trial to determine the influence of heart rate (HR) and blood pressure (BP) on aortic stiffness in response to beta-blockade or angiotensin 2 type 1 receptor antagonism, administered during 24 weeks.Methods:Carotid–femoral pulse wave vel