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A long-term endoprosthesis in which a relatively large part of the surface, which in the implanted condition makes contact with the bone of the wearer of the implant, is provided with electrodes. These electrodes are connected with a source of a low frequency electrical voltage and are so arranged that they alternate with relatively short spacings in the contact zone. The electrode spacing preferably decreases in size in accordance with the size of the mechanical area loading on the corresponding part of the contact area, that is to say, the greater the loading, the smaller the spacing.