4-(4-Alkylpiperazin-1-yl)phenyl Group: A Novel Class of Basic Side Chains for Selective Estrogen Receptor Modulators.
2004
Abstract In the structure–activity relationships of spiro[indene-1,1′-indane] series, the 4-(4-alkylpiperazin-1-yl)phenyl group was found to be functionally equipotent to the 4-(1-piperidinoethoxy)phenyl group, the most widely used basic side chain in selective estrogen receptor modulators.
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