Inflammatory mediator modulation with specific or selective adsorbents

Modulation of inflammatory mediators with specific or selective adsorbents may represent a promising supportive therapy for septic patients. The aims of this study were to compare the influence of specific or selective polymeric adsorbents on endothelial cell activation and to test various adsorbents for binding of high mobility group box 1 (HMGB1), a late mediator in sepsis.