Inclusion Complex of Conjugated Linoleic Acid (CLA) with Cyclodextrins

Conjugated linoleic acid (CLA) inclusion complexes with α-cyclodextrin (α-CD), β-cyclodextrin (β-CD), and γ-cyclodextrin (γ-CD) (designated CLA/CDs inclusion complexes) were prepared to determine the mole ratio of CLA complexed with CDs and the oxidative stability of CLA in the CLA/CDs inclusion complexes. When measured by GC, 1H NMR, and T1 value analyses, 1 mole of CLA was complexed with 5 mol of α-CD, 4 mol of β-CD, and 2 mol of γ-CD. The oxidation of CLA induced at 35 °C for 80 h was completely prevented by the formation of CLA/CDs inclusion complexes. Keywords: Conjugated linoleic acid (CLA); cyclodextrins (CDs); inclusion complexes of CLA with CDs; oxidation