Molecular imaging of tissue with high-contrast multispectral photosensitizing polarimetric imaging techniques

Backscattered laser beam contributions from biological fluids doped with optically active molecules were measured utilizing single-detection autobalanced polarimetric detection principles. The outcome of this study indicates that both the Detective Quantum Efficiency (DQE) and the Degree of Linear polarization (DOLP) of backscattered optical signals increase with increasing the concentrations of molecular optically active dopants. This translates to enhanced signal-to-noise ratio and contrast.