Resolution of total ophthalmoplegia following treatment in a case of nasopharyngeal carcinoma: A case report

Total ophthalmoplegia can occur due to malignancy, inflammation, infection, and trauma. Nasopharyngeal carcinoma is a tumor arising from epithelium of nasopharynx which can spread locally as well as metastasize to distant sites. We report a case of total ophthalmoplegia in a 15-year-old girl which resolved following chemotherapy. She was diagnosed as stage IV B nasopharyngeal carcinoma with left-sided intraorbital extension leading to proptosis and total ophthalmoplegia with preserved optic nerve function. Following 2 months of chemotherapy, a reduction in the size of cervical lymph nodes, proptosis, and total resolution of extraocular movements was noted.