Cardiovascular comorbidity in multiple sclerosis patients treated with Mitoxantrone therapy: a cohort study
2017
Background
Mitoxantrone (MX) has been used as second line therapy for aggressive multiple sclerosis (MS). Potential cardiotoxic effects of MX limit its use; a cumulative dose of up to 100 mg/m2, has been long considered relatively safe. We calculated the frequency of cardiac side effects in MS patients treated with MX.
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