PVA (polyvinyl alcohol) composite aquagel with bioactivity and preparation method thereof

The invention discloses a PVA (polyvinyl alcohol) composite aquagel with bioactivity and a preparation method thereof. The preparation method comprises the following steps: mixing a PVA water solution and a PEO (polyoxyethylene) solution, adding a Ca-ethanol suspension or calcium ethoxide solution, adding anhydrous alcohol containing H3PO4, freezing, and defreezing to obtain the PVA composite aquagel with bioactivity. The invention has the advantages of no biotoxicity of raw materials, low cost, mild reaction conditions, and safe and simple technique, and satisfies the environmental requirements; high number-average molecular weight PEO with favorable biocompatibility and lubricating property is introduced into a nano HA/PVA composite aquagel, so the high number-average molecular weight PEO molecular chain forms polymer brushes on the aquagel surface to lower the friction force of the aquagel surface; and thus, the material can be conveniently applied to joint prosthesis cartilage replacement materials.