α3β1 Integrin-Targeting Polymersomal Docetaxel as an Advanced Nanotherapeutics for Non-Small Cell Lung Cancer Treatment

Yan Zou,Yinping Sun,Beibei Guo,Yaohua Wei,Yifeng Xia,Zhenyuan Huangfu,Fenghua Meng,Jan C. M. van Hest,Jiandong Yuan,Zhiyuan Zhong

α3β1 Integrin-Targeting Polymersomal Docetaxel as an Advanced Nanotherapeutics for Non-Small Cell Lung Cancer Treatment

2020

Yan Zou
Yinping Sun
Beibei Guo
Yaohua Wei
Yifeng Xia
Zhenyuan Huangfu
Fenghua Meng
Jan C. M. van Hest
Jiandong Yuan
Zhiyuan Zhong

Docetaxel (DTX) widely used for treating non-small cell lung cancer (NSCLC) patients is associated with dose-limiting side effects primarily neurotoxicity and myelosuppression. Here, we have develo...

Keywords:

Integrin
Organic chemistry
non small cell
Materials science
Neurotoxicity
Cancer research
Polymersome
Docetaxel
Lung cancer
Chemotherapy
α3β1 integrin

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