Abstract 250: Smad3-Mediated Induction of Smad7 in Activated Myofibroblasts Protects the Remodeling Myocardium

TGFβs are induced in the infarcted and pressure-overloaded myocardium and play an essential role in repair and remodeling by activating Smad-dependent and Smad-independent cascades. Fibroblasts are...