Use of basic fibroblast growth factor following nasal radiofrequency for epistaxis

Objective To explore the effects of basic fibroblast growth factor ( bFGF ) following nasal radiofrequency on repair of nasal mucosa.Methods 93 patients with epistaxis underwent nasal radiofrequency and then were assigned to receive topical use of either oculentum aureomycini ( 35 patients,control group ) or bFGF ( 58 patients,study group ).The efficacy was compared between the two groups.Results There was a significant difference in the cure rate between the study group and the control group ( 91.4％ vs.65.7％,P ＜ 0.05 ).Conclusions bFGF has a promotive effect on repair of nasal mucosa after radiofrequency. Key words: bFGF;  Basic fibroblast growth factor;  Radiofrequency;  Epistaxis