ENDOTHELIAL-SPECIFIC PROMOTER SEQUENCES AND USES THEREOF

The present invention refers to sequences derived from Stabilin-2 promoter to be used as promoter to drive the expression of a gene specifically into endothelial cells, preferably said gene is a therapeutic gene, such as FVIII or any gene involved in the coagulation cascade. Moreover, the invention refers to the use of these sequences for medical purposes, in particular, to treat a genetic disease, such as hemophilia, preferably by gene and/or cellular therapy.