Response to ‘Antinuclear antibodies by indirect immunofluorescence and solid phase assays’ by Bossuyt et al

We would like to thank Dr Bossuyt and colleagues1 for their comments on our article on variability in testing for antinuclear antibodies (ANA).2 This letter, along with previous correspondence,3–9 highlights the many issues about ANA testing and the results obtained with different assay platforms. We agree that a combination of different assays can be a valuable approach to assess more completely the serological …