Regioselective fluoroalkoxylation and polyfluoroalkoxylation of aromatic and heteroaromatic polyhalides

A series of activated polyhalobenzenes and polyhaloheteroaromatic compounds have been reacted with a variety of fluoroalkoxide anions. In most cases, regioselective monosubstitution or polysubstitution was observed. The nature of these monosubstitution and polysubstitution reactions is described.