Plasma Aβ42/40 Ratio Detects Early Stages of Alzheimer’s Disease and Correlates with CSF and Neuroimaging Biomarkers in the AB255 Study

Virginia Pérez-Grijalba,J. Romero,Pedro Pesini,Leticia Sarasa,Inmaculada Monleón,Itziar San José,Javier Arbizu,Pablo Martinez-Lage,Josep Munuera,Amparo Ruiz,Lluís Tárraga,Mercè Boada,Manuel Sarasa

Plasma Aβ42/40 Ratio Detects Early Stages of Alzheimer’s Disease and Correlates with CSF and Neuroimaging Biomarkers in the AB255 Study

2018

Virginia Pérez-Grijalba
J. Romero
Pedro Pesini
Leticia Sarasa
Inmaculada Monleón
Itziar San José
Javier Arbizu
Pablo Martinez-Lage
Josep Munuera
Amparo Ruiz
Lluís Tárraga
Mercè Boada
Manuel Sarasa

Background Easily accessible biomarkers are needed for the early identification of individuals at risk of developing Alzheimer’s disease (AD) in large population screening strategies.

Keywords:

Population
Disease
Neuroimaging
Oncology
Biomarker (medicine)
Internal medicine
Medicine
neuroimaging biomarkers
cognitive decline
large population
Neurology
Cerebrospinal fluid
Dementia

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