Cleido-Cranial Dysplasia: A Case Report

Cleido-Cranial Dysplasia is an autosomal dominant condition with generalised dysplasia of bone and teeth. It is characterized by short stature, typical facial features and skeletal anomalies affecting skull and clavicle. CASE REPORT An 11 year old girl child presented with short stature and abnormal head shape. On examination height was 127 cm and weight was 22.1 kg (both Dr. T. Sathish Kumar, MD, DCH Senior Lecturer, Department of Child Health Christian Medical College, Vellore 632 004 Tamil Nadu. Phone No. 0416 2283348 E mail – sathishkumar@cmcvellore.ac.in References 1. Martin S. Sur Undepacement natural de la clavicle. J Med Chir Pharmacol 1765; 23: 456 2. Marie P, Sainton P. Sur La dysostose cleidocranienne hereditaire. Rev Neurol 1898; 6: 835 3. Gargaya S, Sharma S, Pal LS, Bahl L, Puri DS, Sarin NK. Cleido cranial dysostosis in five generations of a family with some atypical roentgenologic features. Indian Pediatr. 1979; 16 (12):1145-50. 4. Jensen B. Somatic development in cleido-cranial dysostosis. Am J Med Genet 1990; 35: 69-74 5. Nebgen D, Wood RS, Shapiro RD. Management of a mandibular fracture in a patient with cleido-cranial dysplasia. J Oral Maxillofac Surg 1991; 49: 405-409 6. Shapiro IM. Discovery:Osf2/Cbfa 1, a master gene of bone formation. Clin Orthod Res 1999; 2: 42-46 Cleido-Cranial Dysplasia: A Case Report 3 of 3 Author Information T. Kumar Sathish, MD, DCH Lecturer, Department of Child Health,, Christian Medical College Julius Xavier Scott, MD, DCH Lecturer, Department of Child Health,, Christian Medical College Kanagalakshmi, MBBS Clinical Assistant Grade II, Department of SSHS, Christian Medical College