Preparation and Absolute Configurations of Optical Isomers of Sodium 2-[[4-(3-Methoxypropoxy)-3-methylpyridin-2-yl]methylsulfinyl]-1H-benzimidazole (E3810)

The optical isomers of sodium 2-[[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methylsulfinly]-1H-benzimidazole (E3810), a proton pump inhibitor, were separated by HPLC and their absolute configurations were determined by X-ray crystallographic analysis.