Antimutagenesis and anticarcinogenesis mechanisms

This book discusses information regarding: carcinogens and anticarcinogens; cancer and free radicals; alteration of mutagenic potentials by peroxidase, catalase, and superoxide dismutase; effects of vitamins C and E on carcinogen formation and action and relationship to human cancer; interception of toxic agents/mutagens/carcinogens; avoidance of errors after DNA damage; molecular mechanism of adaptive response to alkylating agents; genetic analyses of the roles of UmuDC and MucAB in mutagenesis; mechanisms of spontaneous mutagenesis; inducible cellular responses to DNA damage in mammalian cells; multiple inducible cytochromes P-450 in yeast; mechanisms of carcinogenicity and anticarcinogenicity - role of dietary components; the concentration of bile acids in the fecal stream as a risk factor for colon cancer; dietary promoters nad antipromoters; a mutagen is a mutagen, not necessarily a carcinogen; genetic aspects of cancer epidemiology; inhibitors of mutagenesis and their relevance to carcinogenesis; and population consequences of mutagenesis and antimutagenesis.