Analysis on application of Chinese materia medica in treatment of COVID-19 by suppressing cytokine storm
2020
At the end of December, 2019, a novel coronavirus disease (COVID-19) outbreak was found in China COVID-19 spreads all over 268 countries, and more than 70 000 people got infected till February 23th, 2020 COVID-19 can result in acute respiratory distress syndrome and multiple organ failure due to its strong infectivity and extensive spread These severe complications are believed to be the consequence of cytokine storm caused by the virus infection In the �Diagnosis and treatment of novel coronavirus pneumonia�, glucocorticoid is recommended as the immunosuppressive agents to prevent acute immune reaction in critical patients However, the usage of glucocorticoid may bring severe residual effects such as superinfection risks, prolonged course of disease Traditional Chinese medicine might have advantages in the moderation of immune system Actually, TCM is now applied in the treatment of COVID-19 clinically, and exhibits excellent therapeutic effects In this review, the potential usage of TCM or traditional prescriptions in inhibiting cytokine storm and treating in acute lung injury were analyzed, which would be an effective strategy for the treatment of COVID-19
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