XPO1 inhibitors represent a novel therapeutic option in Adult T-cell Leukemia, triggering p53-mediated caspase-dependent apoptosis.
2021
Vallve, Maria Lourdes Farre. Fundacao Oswaldo Cruz. Instituto Goncalo Moniz. Salvador, BA, Brasil. 1KU Leuven Department of Microbiology, Immunology and Transplantation,
Laboratory of Virology and Chemotherapy, Rega Institute, B-3000 Leuven,
Belgium. 2KU Leuven Department of Microbiology, Immunology and
Transplantation, Laboratory of Clinical and Epidemiological Virology, Rega
Institute, B-3000 Leuven, Belgium. 3Karyopharm Therapeutics, Newton, MA,
USA. 4Instituto de Pesquisa Goncalo Moniz, Oswaldo Cruz Foundation
(FIOCRUZ), Salvador, Bahia, Brazil. 5HUPES, Federal University of Bahia (UFBA),
Salvador-Bahia, Brazil. 6Department of Pathology and Tumor Biology, Kyoto
University, Kyoto, Japan
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