Propolis and honey trigona decrease leptin levels of central obesity patients.

2020 
OBJECTIVE: This study aimed to examine whether honey and propolis Trigona can reduce the level of leptin in central obesity human. METHODS: It was a quasi-experimental study, population and sample were central obesity and normal weight as control. Sample size was 30 participants taken using purposive sampling. RESULTS: Intervention as long as 14 days make an increased level of leptin as many as 97.076pg/ml in control group and decreasing respectively 171.803pg/ml and 245.293pg/ml in honey and propolis intervention group, both significant statistically. The dose of honey given was 105mg/days divided into 3 packs, and each pack contains 35mg. The dose of propolis was 60mg/days and divided into 3 capsules, each of it contains 20mg. Intervention as long as 14 days and leptin levels examined using human ELISA Kit three times, that is before intervention, 7 days after the intervention and 14 days after intervention. CONCLUSION: Honey and propolis Trigona has the ability to decrease leptin level of central obesity participants. These honey bee products are potential to be a dietary supplement for central obesity patients.
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